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Even modest changes to diet could reduce risk of death, study finds – CBS News

Jul, 12th 2017 5:50 pm, Article Recommended by Dr. J. Smith

With more than one-third of U.S. adults suffering from obesity, it’s no surprise that many Americans would benefit from healthier eatinghabits. Fad diets capitalize on our desire for quick results but usually fail in the long run.

Now new research adds to the evidence that a more moderate approach can make a lasting difference.

A study from the Harvard T.H. Chan School of Public Health finds that improving the quality of diet over time, even with modest changes, may significantly reduce the risk of premature death.

Improvements to diet included consuming more whole grains, vegetables, fruits, nuts, and fish and eatingless red and processed meats and sugary beverages.

“Overall, our findings underscore the benefits of healthy eating patterns including the Mediterranean diet and the DASH diet. Our study indicates that even modest improvements in diet quality could meaningfully influence mortality risk and conversely, worsening diet quality may increase the risk,” lead author Mercedes Sotos-Prieto, who worked on the study while a postdoctoral fellow in the Harvard Chan School department of nutrition and who is currently an assistant professor of nutrition at Ohio University, said in a statement.

For the study, published in the New England Journal of Medicine, Sotos-Prieto and her team analyzed data on nearly 74,000 adults over a 12-year period. The researchers assessed the participants’ diet using three different scoring methods: the 2010 Alternate Healthy Eating Index, the Alternate Mediterranean Diet score, and the Dietary Approaches to Stop Hypertension (DASH) diet score. Each model assigns scores to various types of food, with healthier foods receiving higher scores and less healthy foods receiving lower scores.

The results showed that better diet quality over a 12-year period was linked to a reduced risk of death in the subsequent 12 years, no matter which method of scoring was used. Whole grains, fruits, vegetables and fish or n-3 fatty acids appeared to contribute most to an improvement in diet quality.

Specifically, the study showed that a 20-percentile increase in diet-quality scores was associated with an 8 to 17 percent reduction in the risk of death.

That can be achieved, for example, by swapping out just one serving of red or processed meat and replacing it with onedaily serving of nuts or legumes.

In contrast, worsening diet quality was linked to a 6 to 12 percent increase in the risk of death.

Nancy Z. Farrell, a registered dietitian nutritionist and spokesperson for the Academy of Nutrition and Dietetics, said the findings reinforce the work she does every day with her patients.

“Registered dietitian nutritionists practice evidence-based science every day in encouraging and educating the public on disease prevention and treatment, and we know that chronic disease increases the cost of health care and drives up insurance premiums,” she told CBS News.

Farrell says everyone can benefit from making smart diet swaps as often as possible.

“Have a ‘meatless Monday’ dinner where you incorporate beans or legumes, such as red beans and quinoa. Or have a veggie pizza night,” she suggests.

When it comes to snacking, avoid high-calorie junk foods like potato chips and opt for a handful of nuts, or make your own trail mix with nuts, seeds, and dried fruit.

And if you’re looking for a sweet treat, skip the ice cream and try freezing some fruit instead.

“Blueberries or blackberries offer a refreshing summer snack with a burst of coolness,” Farrell said.

Importantly, experts say it’s crucial to not only incorporate such changes into your diet, but to stick with them over time.

“Our results highlight the long-term health benefits of improving diet quality with an emphasis on overall dietary patterns rather than on individual foods or nutrients,” said Frank Hu, professor and chair of the Harvard Chan School department of nutrition and senior author of the study. “A healthy eating pattern can be adopted according to individuals’ food and cultural preferences and health conditions. There is no one-size-fits-all diet.”

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Even modest changes to diet could reduce risk of death, study finds – CBS News

Aaron Rodgers is getting diet tips from his good friend Tom Brady – The Mercury News

Jul, 12th 2017 5:50 pm, Article Recommended by Dr. J. Smith

It sounds like Aaron Rodgers is looking for the kind of career longevity enjoyed by his friend and fellow NFL quarterback Tom Brady.

In an interview with People, Rodgers talked about how clean living was a factor in his 13-year career as a star Green Bay Packers quarterback. The interview took place in advance of Wednesday nights ESPY Awards when the former Cal Golden Bears star competes against the San Mateo-born Brady as the best NFL player of 2017.

Rodgers, 33, opened the interview by dishing just a tiny bit about how hes worked to overcome regrets. He may be referring to his breakup this spring from his high-profile, three-year relationship with actress Olivia Munn, or his longtime estrangement from his Chico-based family, including his younger brother Jordan Rodgers, last years winner of The Bachelorette.

You figure it out as you go, you make mistakes, but being open to those older voices in your life, and those mentors, can help you avoid some of the mistakes that we all [likely] made at a young age, he said.

Thats about as specific as Rodgers would get on that score. He was more specific when he talked about the importance of mentorship and friendship in the sport. Thats where Brady comes in.

The New England Patriots quarterback has become the subject of lengthy profiles in recent years and not just because of his on-field accomplishments: as a four-time Super Bowl MVP who has won five Super Bowls as quarterback. Brady is also said to be playing better than ever, even though hes 39 years old in a rough sport that is notoriously hard on players bodies and brains.

As he enters his 19th season, Bradys fierce attention to his own version of clean living has come under scrutiny.

Brady is known to follow an extremely meticulous diet, fitness and overall life-style regimen that covers everything: what he eats, how he works out or spends his vacation days and even how he sleeps, according to a 2014 profile Sports Illustrated. He is known to follow a strict, mostly vegan diet in which he shuns sugar and alcohol most of the time and in a more extreme way eliminates nightshade veggies like potatoes, tomatoes, eggplant that are said to cause inflammation.

Brady also eats seasonally,meaning he eats certain foods in the winter including red meat and mostly raw food in the summer. Earlier this year Brady launched a plant-based meal kit plan,based on his program, with Purple Carrot.

Rodgers said hes taking some of his nutrition cues from Brady, especially as he contemplates how hell continue to play as he approaches his mid-30s, a time when many quarterbacks begin to contemplate retirement.

I dont have a cookbook out yet, Rodgers joked. And I still have to improve in some areas!

One thing he said he hasnt been able to give up are the nightshade veggies. But he says hes working to improve, mainly because he holds Brady in such high esteem.

I think Tom sets a good example, and we have been friends for a long time and talk about a number of things, Rodgers said. He has kind of set the standard for taking care of your body.

The interview didnt go into whether Rodgers is following some of Bradys other life-style choices, such as doing cognitive exercises before bedtime to destimulate his brain and to fall asleep by 9 p.m., as Sports Illustrated explained. Brady also rarely lifts weights and works out instead using resistance bands. Meanwhile, on vacation, his daily routine is still carefully scripted. He works out twice naps according to a schedule, surfs, avoids alcohol and still goes to bed early.

But Rodgers might have other ways of taking care of his most prized asset his body. In early April, shortly after he broke up with Munn, it was reported that he spends a lot time in Los Angeles, getting weekly facials. He had also been working out at the Unbreakable Performance Center, a gym known in West Hollywood for its celebrity clientele.

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Aaron Rodgers is getting diet tips from his good friend Tom Brady – The Mercury News

Age-old grapefruit diet, healthy or hazardous? – THV 11

Jul, 12th 2017 5:50 pm, Article Recommended by Dr. J. Smith

Old ‘grapefruit diet’ gaining new popularity

Amanda Jaeger , KTHV 10:33 PM. CDT July 11, 2017

Grapefruit Diet, Credit: KTHV

LITTLE ROCK, Ark. (KTHV) – Many fad diets come and go but some seem to stick around through the decades. One of those diets is the grapefruit diet.

It has been around since the 1930s and claimed grapefruits are a type of super food that burn fat and make you lose weight fast. But is there any truth to it?

THV11 spoke with David Rath, a nutritionist for over 20 years. He has seen the grapefruit diet grow and fall in popularity.

Amanda Jaeger & David Rath, Credit: KTHV

The premise behind it is that grapefruit has a substance in it that causes you to lose weight, he said.

People claim grapefruit is so filling, you can only eat so many per day, which means consuming a lot fewer calories. Other variations of the diet call for people to eat at least half a grapefruit or 4 ounces of 100 percent grapefruit juice before each meal to make them less hungry and lose fat. Others claim grapefruits have super enzymes to burn fat.

Rath said most of those claims arent true, but grapefruits do have great qualities for people to consider. Theyre high in Vitamin C, an antioxidant that helps reduce the risk for disease. Theyre low in calories. If you eat the whole fruit, including the pulp, it can help lower your cholesterol.

The catch is those amazing qualities arent only evident in grapefruits. Most fruits and vegetables have some of those qualities.

Credit: KTHV

Fruits and vegetables are about 90 percent water and have a lot of fiber that fills you up without getting you many calories, said Rath.

He added people should absolutely include grapefruits into their diet, as well as other fruits and vegetables and foods from the five major food groups. He said the age-old truth make sure to eat those fruits and veggies really does win. It is the key to making you feel fuller while consuming fewer calories and giving you great nutrients.

But there are dangers with the grapefruit diet models that tout eating grapefruits on overload while skimping out on other healthy foods. Its also dangerous to use any of the grapefruit diet models that recommend eating a low number of calories each day.

It can actually be harmful to your weight loss goals and cause you to go into starvation mode from consuming too few calories, said Rath. Very low-calorie diets make the body think it is starving, which lowers your metabolism, and makes it hard for you to lose weight.

Too many grapefruits and too few calories will also not provide you the nutrition your body needs. Even if your weight drops temporarily, its not going to last and it could cause more damage than you would think.

That type of diet is not sustainable because people aren’t going to eat like that for the rest of their life, he said.

Credit: KTHV

Rath added the best way to stay healthy is to make good meal choices from the five food groups while staying within your recommended calorie level. Its important to incorporate physical activity because that’s another way to burn calories and maintain good fitness levels.

It’s also important to check with your doctor and nutritionist before trying any new diets because they can interact with medication.

Grapefruits, for example, can interact with certain medications and cause serious health issues.

For more information on healthy eating and living just click here.For more information from David Rath, you can visit his website here.

2017 KTHV-TV

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Age-old grapefruit diet, healthy or hazardous? – THV 11

Mackenzie Mckee Tells All About Her New Fitness Program, Diet, & Upcoming Projects! – OK Magazine

Jul, 12th 2017 5:50 pm, Article Recommended by Dr. J. Smith

Mackenzie Mckee was first introduced to the world on the hit MTV series 16 & Pregnant and then Teen Mom 3. But fast-forward a few years later, the now mother-of-three is building her own fitness empire one project at a time.

In an exclusive interview with, the fitness guru opened up about her recently launched and extremely successful fitness program, Body By Mac. Its something Ive dreamed about, she said, especially after being diagnosed with diabetes. Since its Memorial Day weekend launch, she has sold over 1,000 programs and now is working her way up to 2,000! I feel like when it comes to my following, I know my following. Ialready know I target women, its all about learning your followers, she explained of the mega success. The mother-of-three explained that her longest workout is 35 minutes and the best part is, it can be done at home!

As for her plans to keep building her fitness brand, she explained, In the future, I am going to have a monthlysubscription and I will uploadcookingvideos, workout videos targeting different body parts and more. And luckily, fitness fans will not only get a diet and exercise plan! I am starting a clothing line, she revealed. Its all going to beathleticwear. Comfortable fitness clothes!

After welcoming her third child, Mackenzie started getting her pre-baby body back thanks to her diet and exercise routine, but now she stepped up her game to compete in an upcoming body building competition. Forthe first time, Ive hired a trainer, she confessed. I am training for a body building competition. My diet is pretty strict however, I eat more than an average person eats. I meal prep Sundays for the whole week and I stick to my diet 7 days a week, which consists of a lotofgrains and a lotofbroccoli and beans! And a lot of lean meats, egg whites, chicken, white fish, oatmeal with blueberries and plant based protein.

Even though Mackenzie has achieved so much when it comes to her fitness journey, she understands and knows what its like to struggle at first! The hardest part is definitely starting. You begin to look at food aspoisonto your body! Its like my whole day is ruined if Idontwork out. In the beginning I hated running. Once you start and get motivated, you learn to love it. Its hard starting, she explained. We are human, there are days when you have your off days, but its about finding that balance and know when to get back on the grind.

Following the launch of her successful program, she is already working on new features. Idontwant to just train people, I want them to feel better and be happier, the former reality star said.

Kick start your fitness journey today with Mackenzie and purchase Body By Mac right here!

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Mackenzie Mckee Tells All About Her New Fitness Program, Diet, & Upcoming Projects! – OK Magazine

Docs Should Counsel Even Healthy People on Diet, Exercise, Experts Say – Bismarck Tribune

Jul, 12th 2017 5:50 pm, Article Recommended by Dr. J. Smith

TUESDAY, July 11, 2017 (HealthDay News) — Lifestyle counseling could help protect the long-term heart health of adults who aren’t yet at high risk for heart attack and stroke, a panel of medical experts says.

The U.S. Preventive Services Task Force (USPSTF) on Tuesday reaffirmed its 2012 recommendation that doctors consider extra counseling on diet and exercise even among their low-risk patients.

“The Task Force encourages primary care clinicians to talk to their patients about eating healthy and physical activity,” said task force vice chair Susan Curry. If patients are interested and motivated to make lifestyle changes, doctors should offer to refer them to counseling, she said.

Obese people and those who have high blood pressure or cholesterol levels, diabetes, or problems maintaining normal blood sugar levels are at higher risk for heart disease. The USPSTF already advised doctors to offer their high-risk patients intensive behavioral counseling to help prevent heart attack, stroke and other heart-related problems.

This type of counseling involves more than a single conversation during a doctor’s visit. In many cases, patients attend multiple counseling sessions with another health care professional.

In its final recommendation published July 11, the panel concluded that primary care doctors should also consider offering healthy lifestyle behavioral counseling to patients who are at moderate or low risk for heart disease, including those who exercise and have a generally healthy diet.

“This recommendation complements separate task force recommendations for people at increased risk, which recommend behavioral counseling for all high-risk patients,” said Dr. Carol Mangione, a task force member.

The recommendation was published in the Journal of the American Medical Association. It also appears on the USPSTF website.

Cardiovascular disease, which includes heart attacks and strokes, is the leading cause of death in the United States, the panel noted.

See the U.S. Centers for Disease Control and Prevention for more on healthy living.

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Docs Should Counsel Even Healthy People on Diet, Exercise, Experts Say – Bismarck Tribune

Here’s how laxative diets can work against you – Times of India

Jul, 12th 2017 5:49 pm, Article Recommended by Dr. J. Smith

To lose weight is not an easy process, especially if you have been struggling with your weight for years. Sometimes, to lose weight quickly, we end up taking routes that may hurt our body in the long run. Laxative diets are one such method of losing weight. But we should not judge a book by its cover right? Here’s see how laxative diets may hurt your body more than you think. What are laxatives? Laxatives are originally drugs that are meant for those suffering from constipation issues. Laxatives work in your large intestines, while the food is absorbed in your small intestine. When our diet lacks proper intake of vegetables and fruits with the required amount of roughage, we end up being constipated. Laxatives are ideally meant for people suffering with severe constipation, owing to a disease or symptom, that has prolonged for more than four days.

A trend- laxative diet Since laxatives help you poop smoothly, your body ends up losing water. Many people mistake this water loss for weight loss.

“When a party or big celebration approaches, we often want to lose weight. People often take laxatives to get rid of tummy fat for a temporary period of time. What they don’t understand is how it can hurt them in the long run,” says Dr Renu Garg, nutritionist and homeopath. Dr Garg also mentions how dangerous this temporary solution can be if one is in the habit of taking laxatives every now and then.

Experts feel that using laxatives as a permanent solution for weight loss is a huge myth that needs to be busted right away. This is because when we consume laxatives for weight loss, we are damaging our muscles, nerves and digestive tract permanently.

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Here’s how laxative diets can work against you – Times of India

Weight Loss Tip: QUESTION Conventional Thinking on Diet and Exercise! – HuffPost

Jul, 12th 2017 5:49 pm, Article Recommended by Dr. J. Smith

Its a muggy, sunny day here on Long Island, and in a couple of hours, I begin a full afternoon into the evening of clients. I love helping people change their lives by incorporating exercise into their daily lives, and by making simple nutritional tweaks. Because of all the information out there (most of it being bull!), its very easy to get overwhelmed and confused while seeking to improve your health and your weight!

Today, I want to dive deep a little bit about conventional thinking on diet and exercise. Here in the States, its recommended by both the government and the medical establishment that the average person gets an average of 60 minutes of light-to-moderate physical activity per day, and that their diets should be carb-saturated and dependent on calories above all else.

This is what were taught in school growing up, what were told by our doctors, and what most of the people in our lives looking to lose weight and to improve health turn to. The problem is, NEITHER of these common recommendations are accurate, and as a result, there are a lot of folks across the country and around the world that follow this advice to the tee who see little-to-no longterm success.

I should know Ive been there

After struggling with childhood obesity, I decided to pick up a baseball and start playing sports at the ripe old age of 12. Due to my growth spurt, the sudden onset of regular physical activity and my teenage metabolism, I quickly grew into my weight, and then entered college at a lean but muscular six feet tall, 215 lbs.

A common ailment for folks attending university is to put on 15 lbs during their freshman year. I was fortunate that did not happen to me Unfortunately, over the first three months of my sophomore year, I wasnt so lucky:

In just three months, I put on 70 lbs! I was still active, going to the gym five days a week, playing rec sports like basketball, football, and racquetball, and yet, because I never changed a damn thing about my nutrition, it finally caught up to me!

I remember going home for Thanksgiving break towards the end of November, and my family members and home friends asking me, What happened to you?! You were just in shape three months ago! To make matters worse, my school friends began to see all the weight Id put on in my weeklong absence during the holiday, and quickly began ragging on me when we had a few too many to drink back at school.

After the academic year was over, I decided I was going to count calories, reduce portions, and exercise HARD! Following the Food Pyramid (now known as MyPlate), I consumed a diet low in calories, high in healthy grains, vegetables and fruits, and minimized my dietary fat. My gym sessions ramped up from 90 minutes to nearly three hours, and Id often do two-a-days!

For four months, this worked: I lost 40 lbs, and thought I was well on my way to undoing the damage. Unfortunately, this began the longest plateau of my life:-(

For the next TWO years, I didnt lose a pound. I stayed stuck at 235 lbs, and no matter what I did, I just couldnt get under that. I started trying other popular dietary strategies and fitness methodologies with little-to-no success. I damn near gave up

Then, my buddy turned me on to CrossFit. After doing some research, I saw that a lot of CrossFitters subscribe to the Paleo diet. While my nutritional philosophies have evolved a bit since then, this was the first nutritional philosophy Id come across that told me NOT to worry about calories or portions, and to instead worry about WHAT I was eating.

Over the next four months, I lost another 20 lbs, and got back to my original weight when I started my journey. But, I wasnt satisfied! I wanted to look like one of those fitness models in the magazines, and decided to see if there was anything I could do to push the envelope. I was told to get a food allergy test by another acquaintance, and sure enough, found I was allergic to dairy. I cut that out of my regular diet, and another 15 lbs left without even trying! I then learned about lipolysis and keeping your body in a fat-burning state, and it was game, set and match:

Why do I tell you this? Because I wasted TWO YEARS of my life following conventional advice and fad diets with nothing to show for it after the first four months. I really thought I was going to be stuck with this tubby dadbod forever, and that maybe thats just how Im meant to be.

This whole experience really turned me off to listening to conventional thinking, and so I took matters into my own hands: Getting both certified and educated so that I could make the best decisions possible for my health! Now, thats what I do for others, and Im proud that thats the path Ive chosen.

So, if youve been told to watching your portions or to bust your ass for an hour a day, think again! Studies show that types of exercise like interval training can do just as much for you in 10 minutes as a two hour gym session can:-)

Plus, you dont NEED a gym! If going to a gym works for you, great, but Im a huge proponent of working out at home or outdoors. This gives me more flexibility to change things up and work out on MY time, without having to allocate nearly two hours to commuting to and from a gym.

So, do me a favor? Next time an expert tells you to eat a certain way or to do a certain type of exercise, do your homework before you blindly accept his/her recommendations;-)

P.S. If youre READY to take that first step on your health and weight loss journey, then youre REALLY going to want to download my FREE report!

With 10 years of experience, SEVEN different fitness and nutrition certifications, and a sustained weight loss of 100 lbs., I think I know a thing or two about this Permanent Weight Loss thing;-)

This report will provide you with the five strategies I personally used to lose 100 lbs., and KEEP THEM OFF! These are the same five strategies I teach my Permanent Weight Loss clients, and are the basis to losing weight and getting healthy once and for all!

To get your FREE copy, please go to

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Weight Loss Tip: QUESTION Conventional Thinking on Diet and Exercise! – HuffPost

The Biggest Loser: CANCELED By NBC Over Weight Loss Drug Scandal! – The Hollywood Gossip

Jul, 12th 2017 5:49 pm, Article Recommended by Dr. J. Smith

The Biggest Loser has been canceled by NBC, according to multiple media reports and none other than the hit show’s resident doctor.

An incredible 17-season run for TBL on the network has ended following a weight loss drug scandal, the origins of which go back years.

According to Dr. Robert Huizenga, this can be traced back to a former contestant who alleged that participants were given drugs on set.

Ones to make them lose weight, if that wasn’t obvious.

The bombshell revelation was made in court documents in which the doctor accuses a participant of bringing bad publicity to the show.

Last year, Huizenga sued Joelle Gwynn, who appeared on the show in 2008, and the New York Post, over an article implicating him.

Both sources claim the doctor was behind giving participants illegal weight loss pills, and he wasn’t the only player involved, allegedly.

Gwynnalso accused the show’s trainer Bob Harper of supplying contestants with Adderall, a drug prescribed to patients with ADHD.

Adderallis also known to suppress appetite; Harper also supplied, allegedly, pills containing ephedra extract, which is banned by the FDA.

She told the New York Post that the pills left her “jittery and hyper” and alleged that he approved the distribution of the pills on the show.

Gwynn, along with other past contestants, also claimed they were encouraged to lie about their calorie intake during the NBC program.

As a result, multiple reality stars have said that after the competition, they quickly gained back all the weight as a result of the regimen.

Gwynn told the newspaper last year:

“People chastise Bill Cosby for allegedly offering meds to women, but it’s acceptable to do to fat people to make them lose weight.”

“I feel like we got raped, too.”

For his part,Huizenga has denied all allegations and has filed a lawsuit stating the story was “fabricated, fictitious and outright libelous.”

“Nothing could be further from the truth,” he says.

He calls himself “a world-renowned health expert and esteemed sports doctor who advocates for safe and effective weight loss methods.”

Gwynn fired back, reaffirming her statements on the record, and demanded his suit be thrown out and that the doctor pay her legal fees.

In new court documents,Huizengademands thatGwynn’s motion be denied, by virtue of her public comments getting the show axed.

Gwynn’s”outrageous” accusations, his lawyer says, “resulted in the cancelation of The Biggest Loser” and other opportunities for him.

This is particularly egregious for Dr. Huizenga (above), he says, because of his “strict life-long anti-drug beliefs and strict anti-drug policy.”

On The Biggest Loser, he wouldn’t even allow contestants to take “caffeine pills or drink more than one cup of coffee, much less illegal drugs.”

Though Gwynn never named names, his legal team claims that a “defamed person need not be named in the defamatory words” necessarily.

If the statements are enough to identify him, it’s all academic, he says, and it was enough to cost him multiple other TV show opportunities.

Season 17 of the show aired last year, after which NBC did not publicly announce a decision on future installments of The Biggest Loser.

NBC has yet to formally announce the cancelation.

Continued here:
The Biggest Loser: CANCELED By NBC Over Weight Loss Drug Scandal! – The Hollywood Gossip

San Diego start-ups navigate mixed venture capital landscape in … – The San Diego Union-Tribune

Jul, 12th 2017 5:49 pm, Article Recommended by Dr. J. Smith

San Diego start-ups raised a solid amount of venture capital in the second quarter this year compared with a year earlier signaling a good but not great fundraising environment for local entrepreneurs.

Two reports out this week the PitchBook/National Venture Capital Association Venture Monitor study and the PricewaterhouseCoopers/CB Insights MoneyTree report showed that more San Diego County start-ups raised money in the second quarter than in same quarter the prior year.

But even though more firms took in capital, the overall amount raised locally fell short of totals from the second quarter of 2016.

The PitchBook report found 61 local companies raised $406 million, compared with 42 companies netting $411 million a year earlier.

MoneyTree pegged a similar trend, with 24 companies raising $287 million in the second quarter, compared with 22 firms pulling in $389 million a year ago.

San Diego venture capital climate last quarter bucked the nationwide trend of not only less dollars but also fewer deals for start-ups compared with the second quartter of 2016.

I think it is encouraging to see the number of deals (in San Diego) at a reasonable level. Thats a good sign, said Ryan Spencer, a partner with PricewaterhouseCoopers. In terms of dollars, when you are comparing year over year, we had a couple of mega-deals in the first half of 2016 that we havent seen this year.

In the second quarter last year, genomics biotech Human Longevity raised $220 million.

In San Diego, there is a growing convergence between the regions traditional biotech/pharmaceutical industries and its software/technology firms, said Spencer.

Edico Genome, for example, is a technology company that makes a high speed computer processing platform. But its product is tailored to speed up delivery of gene sequencing data in healthcare.

There are three companies in the top 10 deals that we think are best classified as software or internet, but those companies are related in some way to life sciences, said Spencer.

The PitchBook/NVCA Venture Monitor and MoneyTree reports contain differences for several reasons, including that PitchBook captures money raised by start-ups from angel investors.

There is plenty of capital available for start-ups, as venture capital funds have raised $130 billion since 2014, according to PitchBook.

The story over the last couple of years has been deal flow continued to decline, said Nizar Tarhuni, analytics manager for Seattle-based PitchBook. The bulk of that decline has been isolated at the angel and seed level, where we have seen those rounds fall off. But across Series A and up to later stage rounds, it has actually remained fairly steady.

For some angel backed start-ups, it has been difficult to make the jump from individual investors to their first round of institutional venture capital, said Tarhuni.

That has resulted in angel investors being a bit more careful in how they deploy capital (in companies) to make sure they make the cut in a very competitive market looking for investment at the Series A or Series B level, he said.

Nationwide, PitchBooks Venture Monitor had 1,958 companies raising $21.78 billion in the second quarter. Thats down from 2,162 companies raising $23 billion in the same quarter last year.

In the quarter, mega-deals for more established companies led the way, according to PitchBook. Thirty-four companies raised at least $100 million in the quarter. None were based in San Diego.

The MoneyTree report found 1,152 companies raised $18.4 billion in the quarter nationwide again down from 1,495 firms taking in $21 billion a year earlier.

One of the strongest industries this quarter nationally was digital health, which recorded 113 deals for $2.7 billion, according to the MoneyTree report. Six digital health companies rung up mega-rounds of $100 million or more in the quarter.;



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San Diego start-ups navigate mixed venture capital landscape in … – The San Diego Union-Tribune

Want to live forever? Science thinks that might be possible – Eyewitness News

Jul, 12th 2017 5:49 pm, Article Recommended by Dr. J. Smith

So few people have exceeded that age, in fact, that a group of researchers published an analysisin the journal Nature last year arguing that the human species’ lifespan plateaus around 115.

FILE: An elderly resident from the Cape Peninsula Organisation for the Aged holds her ID before casting her special vote on 17 May 2011. Picture: EWN

Jeanne Calment, the French woman who holds the record for the longest verified lifespan, died in 1997 at 122-years-old.

Few people, of course, ever become supercentenarians, 110-years-old or older, and even fewer hit 115.

So few people have exceeded that age, in fact, that a group of researchers published an analysis in the journal Nature last year arguing that the human species’ lifespan plateaus around 115.

But a number of scientists are now rebutting that analysis with five separate commentaries published in Nature on 28 June.

The authors of these pieces argue that the original analysis relied on statistics that were incomplete or analysed in a way that led to a false conclusion. They suggest two alternatives: We either don’t have enough data to know if the human lifespan has a limit, or the plateau is closer to 125 than 115.

“The available data are limited, there aren’t that many supercentenarians,” Maarten Pieter Rozing, a professor at the University of Copenhagen who co-authored one commentary, told The Scientist. “And I think there are no strong arguments that show there is a decline [in the rate at which lifespans are increasing].”


Life expectancy has crept up fairly steadily over the past 150 years or so. But Xiao Dong, Brandon Milholland, and Jan Vijg, the authors of the original analysis, argue that comparing the life expectancy of supercentenarians to the age at which they died can reveal the natural limit of the human lifespan.

The scientists used data on maximum reported age at death split into two sets based on supercentenarians from the US, UK, Japan, and France. The first set covered deaths from 1968 to 1994 – a period when the maximum age was inching up. But by the time covered in the next dataset, from 1995 to 2006, the age seemed to plateau or even slightly be on the decline (exceptions like Calment aside).

Life expectancy, however, rose throughout both time periods. The scientists, therefore, concluded that because humans’ maximum age didn’t keep rising with life expectancy, it appeared a limit had been reached.

Even if we were to cure various diseases like cancer or Alzheimer’s, those scientists still claimed that humans would probably be unlikely to live past 115. And they put the chances of a person live past 125 at less than 1 in 10,000.


The authors of the recent rebuttals say that because there are so few supercentenarians out there, the number of deaths for this age group between 1995 and 2006 is too small to yield reliable conclusions. There just haven’t been enough supercentenarians to really pinpoint a maximum age.

As people live longer, it’s likely that more will push past that supposed limit, the authors of the rebuttals argue – it’ll just take time to get there.

“[T]he idea of a set limit to human longevity is not strongly supported by what is being discovered about the biology of ageing,” Rozing and his co-authors wrote in their commentary.

“The continuing increase in human life expectancy that has occurred over recent decades was unforeseen. It provides evidence for greater malleability of human ageing than was originally thought.”

Over the span of human history, many of the lifespan increases we’ve seen would have been unimaginable at some point. Those living 200 years ago, for example, would have thought it was crazy that people could regularly live to be 80. Yet here we are.

Rozing told The Scientist that there’s an easy way to find out whose hypothesis is correct about the maximum lifespan.

“[W]e can just wait and see who’s right,” he said.

Written by Kevin Loria.

This article was republished courtesy of the World Economic Forum.

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Want to live forever? Science thinks that might be possible – Eyewitness News